|
|
8,11,14-eicosatrienoic_acid + O2 + ferricytochrome_b5 + H+ <=> Arachidonoyl-CoA + H2O + ferricytochrome_b5
|
1.14.19.44
acyl-CoA (8-3)-desaturase
|
–
|
MK
|
| |
BRENDA:
BR51508;
BS433635
KEGG:
R11059
MetaCyc:
RXN-16064
|
|
|
|
8,11,14-eicosatrienoic_acid + H2O <=> 8,11,14-eicosatrienoic_acid + CoA + H+
|
3.1.2.2
palmitoyl-CoA hydrolase
|
–
|
K
|
| |
KEGG:
R08182
MetaCyc:
RXN-13435
|
|
|
|
(11Z,14Z)-icosa-11,14-dienoyl-CoA + O2 + ferricytochrome_b5 + H+ <=> 8,11,14-eicosatrienoic_acid + H2O + ferricytochrome_b5
|
1.14.19
1.14.19.3
acyl-CoA 6-desaturase
|
–
–
|
MK
|
| |
KEGG:
R12171
MetaCyc:
RXN-17105
|
|
|
|
(2E,8Z,11Z,14Z)-icosatetraenoyl-CoA + NADH + H+ <=> 8,11,14-eicosatrienoic_acid + NAD+
|
1.3.1.93
very-long-chain enoyl-CoA reductase
|
–
|
M
|
| |
MetaCyc:
RXN-12971
|
|
|
|
dihomo_gamma_linolenoyl_[acp] + H2O <=> 8,11,14-eicosatrienoic_acid + [acyl-carrier_protein] + H+
|
3.1.2.14
oleoyl-[acyl-carrier-protein] hydrolase
|
–
|
|
| |
MetaCyc:
RXN-12973
|
|
|
|
8,11,14-eicosatrienoic_acid + glycerolipid <=> [glycerolipid]-di-homo-gamma-linolenate + CoA
|
2.3.1.23
1-acylglycerophosphocholine O-acyltransferase
|
–
|
M
|
| |
MetaCyc:
RXN-16044
|
|
|
|
8,11,14-eicosatrienoic_acid + O2 <=> (8Z,11Z,14Z)-8-hydroxyeicosa-8,11,14-trienoic_acid
|
1.13.11.60
linoleate 8R-lipoxygenase
|
–
|
|
| |
BRENDA:
BS445450
|
|
|
|
8,11,14-eicosatrienoic_acid + ferricytochrome_b5 + O2 + H+ <=> arachidonic_acid + ferricytochrome_b5 + H2O
|
1.14.19.30
acyl-lipid (8-3)-desaturase
1.14.19.44
acyl-CoA (8-3)-desaturase
|
–
–
|
B
|
| |
BRENDA:
BS432765
|
|
|
|
eicosadienoic_acid + reduced_acceptor + O2 <=> 8,11,14-eicosatrienoic_acid + acceptor + H2O
|
1.14.19.4
acyl-lipid (11-3)-desaturase
|
–
|
|
| |
BRENDA:
BS375572
|
|
|
|
8,11,14-eicosatrienoic_acid + diacylglycerol <=> CoA + 1,2-diacyl-3-dihomo-gamma-linolenoylglycerol
|
2.3.1.20
diacylglycerol O-acyltransferase
|
–
|
|
| |
BRENDA:
BS455583
|
|
|
|
8,11,14-eicosatrienoic_acid + O2 <=> 12-hydroxyeicosatrienoic_acid
|
1.13.11.31
arachidonate 12-lipoxygenase
|
–
|
|
| |
BRENDA:
BS260724
|
|
|
|
8,11,14-eicosatrienoic_acid + O2 <=> 8-hydroxydihomo-gamma-linolenic_acid
|
1.13.11.60
linoleate 8R-lipoxygenase
|
–
|
|
| |
BRENDA:
BS441310
|
|
|
|
8,11,14-eicosatrienoic_acid + O2 <=> 15-hydroperoxy-8,11,13-eicosatrienoic_acid
|
1.13.11.33
arachidonate 15-lipoxygenase
|
–
|
|
| |
BRENDA:
BS355927
|
|
|
|
ATP + 8,11,14-eicosatrienoic_acid + CoA <=> AMP + diphosphate + 8,11,14-eicosatrienoyl-CoA
|
6.2.1.15
arachidonate---CoA ligase
|
–
|
|
| |
BRENDA:
BS177
|
|
|
|
ATP + 8,11,14-eicosatrienoic_acid + CoA <=> AMP + diphosphate + 8,11,14-eicosatrienoic_acid
|
6.2.1.3
long-chain-fatty-acid---CoA ligase
|
–
|
B
|
| |
BRENDA:
BS443134
|
|
|
|
8,11,14-eicosatrienamide + H2O <=> 8,11,14-eicosatrienoic_acid + NH3
|
3.5.1.99
fatty acid amide hydrolase
|
–
|
|
| |
BRENDA:
BS399793
|
|
|
|
O2 + 8,11,14-eicosatrienoic_acid <=> (8Z,10E,14Z)-(12S)-12-Hydroperoxyeicosa-8,10,14-trienoate
|
1.13.11.31
arachidonate 12-lipoxygenase
|
–
|
|
| |
SABIO-RK:
14338
|
|
